id: Pfam:PF02696
pfam_id: PF02696
name: Protein adenylyltransferase SelO
short_name: SelO
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02696
counters:
  proteins: 14609
  matches: 14895
  proteomes: 12188
  taxa: 20440
  structures: 8
  alphafold_models: 10025
  domain_architectures: 74
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR003846
description: SelO and its homologues are widespread among most eukaryotic taxa, and are also common in
  many major bacterial taxa. SelO is a conserved pseudokinase that transfers AMP from ATP to Ser, Thr,
  and Tyr residues on protein substrates (AMPylation). It contains a protein kinase fold with ATP flipped
  in the active site [[cite:PUB00092455]]. In eukaryotes, it is a mitochondrial protein that may be involved
  in redox biology [[cite:PUB00092456]].