id: Pfam:PF02958
pfam_id: PF02958
name: Ecdysteroid kinase-like family
short_name: EcKL
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02958
counters:
  proteins: 11893
  matches: 13042
  proteomes: 2359
  taxa: 5457
  structures: 0
  alphafold_models: 9868
  domain_architectures: 210
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR004119
description: This family includes ecdysteroid 22-kinase, an enzyme responsible for the phosphorylation
  of ecdysteroids (insect growth and moulting hormones) at C-22, to form physiologically inactive ecdysteroid
  22-phosphates [[cite:PUB00091343]]. Most insects contain 12 to 105 genes encoding this family and yet
  so far only one enzyme (ecdysteroid 22-kinase from Bombyx mori) has characterised substrates (2-deoxyecdysone,
  ecdysone, 20-hydroxyecdysone). There are good reasons to believe that this family includes kinases that
  act on other small molecule substrates and that they may function in detoxification processes [[cite:PUB00094481]].