id: Pfam:PF03003
pfam_id: PF03003
name: Pox virus entry-fusion-complex G9/A16
short_name: Pox_G9-A16
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF03003
counters:
  proteins: 206
  matches: 206
  proteomes: 85
  taxa: 219
  structures: 12
  alphafold_models: 176
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR004251
description: Pox_G9-A16 is a family of two of the eight entry-fusion complex proteins of pox viruses.
  the viral fusion proteins are components of the mature virion, MV, membrane. Extracellular enveloped
  virions (EVs), the infecting particles are MVs with an additional membrane that is opened or removed
  prior to the fusion of the MV and cell membrane during virus entry. G9 and A16 interact closely with
  each other and each is required for membrane fusion and virus entry as well as for interaction with
  A56/K2 [[cite:PUB00078710]].