id: Pfam:PF03724
pfam_id: PF03724
name: META domain
short_name: META
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF03724
counters:
  proteins: 11140
  matches: 12776
  proteomes: 7924
  taxa: 10868
  structures: 2
  alphafold_models: 6968
  domain_architectures: 94
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR005184
description: Small domain family found in proteins of of unknown function. Some are secreted (e.g. [swissprot:O25998])
  and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression
  in L.amazonensis increases virulence ([swissprot:O43987]; [[cite:PUB00016654]]). A pair of cysteine
  residues show correlated conservation, suggesting that they form a disulphide bond.