id: Pfam:PF03928
pfam_id: PF03928
name: Haem degrading protein HbpS-like
short_name: HbpS-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF03928
counters:
  proteins: 17179
  matches: 17413
  proteomes: 9798
  taxa: 14541
  structures: 10
  alphafold_models: 10836
  domain_architectures: 65
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR005624
description: This entry includes haem degrading protein HbpS from Streptomyces reticuli (swiss:Q9RIM2)
  and and GlcG from Escherichia coli [[cite:PUB00007282]]. HbpS is up-regulated in response to haemin-
  and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction
  system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein [[cite:PUB00052019]].
  The structure of GlcG is composed of an alpha-beta(2)-alpha(3)-beta(2)-alpha fold, similar to the Roadblock/LC7
  domain.