id: Pfam:PF04037
pfam_id: PF04037
name: Domain of unknown function (DUF382)
short_name: DUF382
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04037
counters:
  proteins: 4347
  matches: 4397
  proteomes: 3033
  taxa: 8016
  structures: 57
  alphafold_models: 3682
  domain_architectures: 60
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007180
description: This domain is specific to the human splicing factor 3b subunit 2 and it's orthologues. Splicing
  factor 3b subunit 2 or SAP145 is a suppressor of U2 snRNA mutations. Pre-mRNA splicing is catalysed
  by a large ribonucleoprotein complex called the spliceosome. Spliceosomes are multi-component enzymes
  that catalyse pre-mRNA splicing and form step-wise by the ordered interaction of UsnRNPs and non-snRNP
  proteins with short conserved regions of the pre-mRNA at the 5' and 3' splice sites and branch site
  [[cite:PUB00013034]].