id: Pfam:PF04126
pfam_id: PF04126
name: Cyclophilin-like
short_name: Cyclophil_like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04126
counters:
  proteins: 564
  matches: 565
  proteomes: 531
  taxa: 1025
  structures: 3
  alphafold_models: 389
  domain_architectures: 6
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025658
description: This domain has a cyclophilin-like fold, consisting of an eight-stranded beta-barrel with
  an alpha helix located between the beta-2 and beta-3 strands and a 310 helix located between the beta-7
  and beta-8 strands. The catalytic site found in human cyclophilin is not conserved in this domain, suggesting
  a different function for this domain [[cite:PUB00039053],[cite:PUB00048358]].