id: Pfam:PF04174
pfam_id: PF04174
name: A circularly permuted ATPgrasp
short_name: CP_ATPgrasp_1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04174
counters:
  proteins: 411
  matches: 412
  proteomes: 325
  taxa: 554
  structures: 0
  alphafold_models: 306
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007302
description: An ATP-grasp family that is present both as catalytically active and inactive versions. Contextual
  analysis suggests that it functions in a distinct peptide synthesis/modification system that additionally
  contains a transglutaminase, an NTN-hydrolase, the Alpha-E domain, and a transglutaminase fused N-terminal
  to a circularly permuted COOH-NH2 ligase. The inactive forms are often fused N-terminal to the Alpha-E
  domain [[cite:PUB00057486]].