id: Pfam:PF04181
pfam_id: PF04181
name: Rtr1/RPAP2 family
short_name: RPAP2_Rtr1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04181
counters:
  proteins: 3353
  matches: 3353
  proteomes: 2673
  taxa: 7179
  structures: 5
  alphafold_models: 2833
  domain_architectures: 54
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007308
description: This family includes the human RPAP2 (RNAP II associated polypeptide) protein and the yeast
  Rtr1 protein [[cite:PUB00045120]]. It has been suggested that this family of proteins are regulators
  of core RNA polymerase II function [[cite:PUB00045120]].