id: Pfam:PF04221
pfam_id: PF04221
name: RelB antitoxin
short_name: RelB
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04221
counters:
  proteins: 5136
  matches: 5146
  proteomes: 2954
  taxa: 5105
  structures: 6
  alphafold_models: 3438
  domain_architectures: 14
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007337
description: RelE and RelB form a toxin-antitoxin system. RelE represses translation, probably through
  binding ribosomes ([[cite:PUB00009906]], [[cite:PUB00009907]]). RelB stably binds RelE, presumably deactivating
  it.