id: Pfam:PF04222
pfam_id: PF04222
name: Protein of unknown function (DUF416)
short_name: DUF416
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04222
counters:
  proteins: 1714
  matches: 1714
  proteomes: 1695
  taxa: 2489
  structures: 2
  alphafold_models: 1089
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007338
description: This is a bacterial protein family of unknown function. Proteins in this family adopt an
  alpha helical structure. Genome context analysis has suggested a high probability of a functional association
  with histidine kinases, which implicates proteins in this family to play a role in signalling (information
  from TOPSAN 2Q9R).