id: Pfam:PF04258
pfam_id: PF04258
name: Signal peptide peptidase
short_name: Peptidase_A22B
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04258
counters:
  proteins: 13660
  matches: 14137
  proteomes: 3348
  taxa: 8908
  structures: 2
  alphafold_models: 11659
  domain_architectures: 192
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR064098
description: The members of this family are membrane proteins. In some proteins this region is found associated
  with [pfam:PF02225]. This family corresponds with Merops subfamily A22B, the type example of which is
  signal peptide peptidase. There is a sequence-similarity relationship with [pfam:PF01080].