id: Pfam:PF04283
pfam_id: PF04283
name: Archaeal Chemotaxis signal transduction system protein F
short_name: CheF-arch
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04283
counters:
  proteins: 591
  matches: 591
  proteomes: 270
  taxa: 468
  structures: 1
  alphafold_models: 546
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007381
description: This is a family of proteins that are archaea-specific components of the bacterial-like chemotaxis
  signal transduction system of archaea. In H. salinarum, the CheF proteins interact with the chemotaxis
  proteins CheY, CheD and CheC2 as well as the flagella-accessory proteins FlaCE and FlaD, and are essential
  for any tactic response. CheF probably functions at the interface between the bacterial-like chemotaxis
  signal transduction system and the archaeal flagellar apparatus. This region is predicted to contain
  a tandem of two PH-like domains.