id: Pfam:PF04301
pfam_id: PF04301
name: Pimeloyl-ACP methyl esterase BioG
short_name: BioG
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04301
counters:
  proteins: 460
  matches: 461
  proteomes: 457
  taxa: 821
  structures: 2
  alphafold_models: 323
  domain_architectures: 6
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007398
description: This protein family includes Pimeloyl-ACP methyl esterase BioG from Haemophilus influenzae
  ([swissprot:P44251]) and similar bacterial proteins. This enzyme is involved in the biosynthesis of
  pymeloyl-ACP and, hence, in biotin biosynthesis. It is organised into a a core domain formed by a seven-stranded
  beta-sheet and a lid domain consisting of four alpha-helices [[cite:PUB00100663]].