id: Pfam:PF04308
pfam_id: PF04308
name: Ribonuclease H-like
short_name: RNaseH_like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04308
counters:
  proteins: 1335
  matches: 1336
  proteomes: 1273
  taxa: 1920
  structures: 0
  alphafold_models: 906
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007405
description: RNaseH_like is a family of uncharacterised eubacterial proteins that are distant homologues
  of Ribonuclease H-like. The family maintains all the core secondary structure elements of the RNase
  H-like fold and shares several conserved, presumably active site residues with RNase HI. This finding
  suggests that it functions as a nuclease [[cite:PUB00020735]].