id: Pfam:PF04327
pfam_id: PF04327
name: Cysteine protease Prp
short_name: Peptidase_Prp
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04327
counters:
  proteins: 3437
  matches: 3437
  proteomes: 3303
  taxa: 4959
  structures: 7
  alphafold_models: 2293
  domain_architectures: 8
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007422
description: This is a family of cysteine protease that are found to cleave the N-terminus extension of
  ribosomal subunit L27 in eubacteria. Proteins in this family are distinguished by a pair of invariant
  histidine and cysteine residues with conserved spacing that form the classic catalytic dyad of a cysteine
  protease [[cite:PUB00075697]].