id: Pfam:PF04366
pfam_id: PF04366
name: Las17-binding protein actin regulator
short_name: Ysc84
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04366
counters:
  proteins: 11690
  matches: 11738
  proteomes: 5737
  taxa: 11239
  structures: 1
  alphafold_models: 9138
  domain_architectures: 156
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007461
description: Ysc84 is a family of Las17-binding proteins found in metazoa. Together, Las17 and Ysc84 are
  essential for proper polymerisation of actin; Ysc84 is able to bind to and stabilise the actin dimer
  presented by Las17 and thereby promote polymerisation. An active actin cytoskeleton is necessary for
  adequate endocytosis. ([pfam:PF00018]), or a FYVE zinc finger ([pfam:PF01363]).