id: Pfam:PF04390
pfam_id: PF04390
name: Lipopolysaccharide-assembly
short_name: LptE
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04390
counters:
  proteins: 8831
  matches: 8831
  proteomes: 8765
  taxa: 12339
  structures: 39
  alphafold_models: 5850
  domain_architectures: 10
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007485
description: LptE (formerly known as RplB) is involved in lipopolysaccharide-assembly on the outer membrane
  of Gram-negative organisms. The lipopolysaccharide component of the outer bacterial membrane is transported
  from its source of origin to the outer membrane by a set of proteins constituting a transport machinery
  that is made up of LptA, LptB, LptC, LptD, LptE. LptD appears to be anchored in the outer membrane,
  and LptE forms a complex with it. This part of the machinery complex is involved in the assembly of
  lipopolysaccharide in the outer leaflet of the outer membrane [[cite:PUB00053165]].