id: Pfam:PF04393
pfam_id: PF04393
name: Protein of unknown function (DUF535)
short_name: DUF535
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04393
counters:
  proteins: 1600
  matches: 1616
  proteomes: 1234
  taxa: 1826
  structures: 0
  alphafold_models: 913
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007488
description: Family member Shigella flexneri VirK ([swissprot:Q99QA5]) is a virulence protein required
  for the expression, or correct membrane localisation of IcsA (VirG) on the bacterial cell surface [[cite:PUB00009979]],
  [[cite:PUB00009980]]. This family also includes Pasteurella haemolytica lapB ([swissprot:P32181]), which
  is thought to be membrane-associated.