id: Pfam:PF04452
pfam_id: PF04452
name: RNA methyltransferase domain
short_name: Methyltrans_RNA
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04452
counters:
  proteins: 19573
  matches: 19706
  proteomes: 17840
  taxa: 25738
  structures: 16
  alphafold_models: 12672
  domain_architectures: 35
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR046886
description: RNA methyltransferases modify nucleotides during ribosomal RNA maturation in a site-specific
  manner. The Escherichia coli member is specific for U1498 methylation [[cite:PUB00058164]][[cite:PUB00044729]].