id: Pfam:PF04463
pfam_id: PF04463
name: 2-thiouracil desulfurase
short_name: 2-thiour_desulf
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04463
counters:
  proteins: 6456
  matches: 6456
  proteomes: 5023
  taxa: 7714
  structures: 5
  alphafold_models: 4053
  domain_architectures: 21
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007553
description: This family of proteins, predominantly found in Bacteria, are involved in the desulfuration
  of 2-thiouracil into uracil in the 2-thiouridine degradation pathway. It has been demonstrated that
  these proteins contain a Fe-S cluster required for their activity [[cite:PUB00098595]].