id: Pfam:PF04502
pfam_id: PF04502
name: Saf4/Yju2 protein
short_name: Saf4_Yju2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04502
counters:
  proteins: 8144
  matches: 8272
  proteomes: 3422
  taxa: 9061
  structures: 12
  alphafold_models: 6907
  domain_architectures: 138
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007590
description: This is a family of eukaryotic proteins that includes CCDC130 and CCDC94 from humans, Saf4
  from fission yeasts and Yju2 from budding yeasts. Saf4 (also known as cwc16) is involved in mRNA splicing
  where it associates with cdc5 and the other cwf proteins as part of the spliceosome [[cite:PUB00008533]].
  Yju2 is a splicing factor that is associated with the Prp 19-associated complex and acts after Prp2
  in promoting the first catalytic reaction of pre-mRNA splicing [[cite:PUB00079198]].