id: Pfam:PF04519
pfam_id: PF04519
name: Polymer-forming cytoskeletal
short_name: Bactofilin
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04519
counters:
  proteins: 9607
  matches: 9649
  proteomes: 6945
  taxa: 10792
  structures: 3
  alphafold_models: 6555
  domain_architectures: 35
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007607
description: This is a family of bactofilins, a functionally diverse class of cytoskeletal, polymer-forming,
  proteins that is widely conserved among bacteria. In the example species C. crescentus, two bactofilins
  assemble into a membrane-associated laminar structure that shows cell-cycle-dependent polar localisation
  and acts as a platform for the recruitment of a cell wall biosynthetic enzyme involved in polar morphogenesis.
  Bactofilins display distinct subcellular distributions and dynamics in different bacterial species,
  suggesting that they are versatile structural elements that have adopted a range of different cellular
  functions.
