id: Pfam:PF04652
pfam_id: PF04652
name: Vta1 like
short_name: Vta1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04652
counters:
  proteins: 7394
  matches: 7431
  proteomes: 3259
  taxa: 8687
  structures: 12
  alphafold_models: 4159
  domain_architectures: 146
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR039431
description: Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that
  is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex
  required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity
  through its conserved Vta1/SBP1/LIP5 region [[cite:PUB00044969]].