id: Pfam:PF04669
pfam_id: PF04669
name: PBDC1 protein
short_name: PBDC1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04669
counters:
  proteins: 3007
  matches: 3036
  proteomes: 2606
  taxa: 6858
  structures: 1
  alphafold_models: 2555
  domain_architectures: 47
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021148
description: This entry includes PBDC1 protein from mammals and its homologues from fungi. PBDC1 homolog
  from S. cerevisiae also known as Ypl225w (Chp1, Chaperone 1 for eEF1A) functions as a co-translational
  chaperone by forming dual interactions with the eEF1A G domain nascent chain and the UBA domain of ribosome-bound
  nascent polypeptide-associated complex [[cite:PUB00160075]]. This protein primes the eEF1A nascent chains
  for binding to GTP as part of a folding mechanism which is tightly coupled to chaperone recycling [[cite:PUB00160075]].