id: Pfam:PF04678
pfam_id: PF04678
name: Mitochondrial calcium uniporter
short_name: MCU
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04678
counters:
  proteins: 6482
  matches: 6501
  proteomes: 2787
  taxa: 7574
  structures: 16
  alphafold_models: 5562
  domain_architectures: 74
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR006769
description: MCU functions with MICU1, an essential gatekeeper component of calcium-channel transport,
  to facilitate Ca2+ uptake into the mitochondrion [[cite:PUB00088836],[cite:PUB00109160],[cite:PUB00081393]].