id: Pfam:PF04765
pfam_id: PF04765
name: TOD1/MUCI70, glycosyltransferase-like domain
short_name: TOD1_MUCI70
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04765
counters:
  proteins: 5489
  matches: 5706
  proteomes: 686
  taxa: 1874
  structures: 0
  alphafold_models: 4377
  domain_architectures: 126
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR048354
description: This entry represents a glycosyltransferase-like domain found in alkaline ceramidase TOD1
  and the probable hexosyltransferase MUCI70 from Arabidopsis. MUCI70 is a predicted glycosyltransferase
  essential for the accumulation of seed mucilage, a gelatinous wall rich in unbranched rhamnogalacturonan
  I (RG I), and for shaping the surface morphology of seeds [[cite:PUB00095110],[cite:PUB00101913]]. TOD1
  is an endoplasmic reticulum ceramidase that catalyses the hydrolysis of ceramides into sphingosine and
  free fatty acids at alkaline pH (e.g. pH 9.5) [[cite:PUB00101912],[cite:PUB00101914]].