id: Pfam:PF04802
pfam_id: PF04802
name: Phosphatase 4 regulatory subunit 3
short_name: PP4R3
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04802
counters:
  proteins: 7072
  matches: 7908
  proteomes: 3343
  taxa: 8840
  structures: 0
  alphafold_models: 5987
  domain_architectures: 100
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR006887
description: This entry represents the Serine/threonine-protein phosphatase 4 regulatory subunit 3 (also
  known as SMEK homologue) PP4R3, which forms a complex with the phosphatase 4 catalytic subunit (PP4c),
  localising it to the DNA damage repair machinery [[cite:PUB00101025],[cite:PUB00035452],[cite:PUB00101024],[cite:PUB00101026]]
  and regulates its activity. PP4c is involved in developmental progression, chemotaxis, expression of
  stress response genes and cell movement. These proteins contain an N-terminal EVH1 domain and this alpha
  solenoid region.