id: Pfam:PF04828
pfam_id: PF04828
name: Glutathione-dependent formaldehyde-activating enzyme
short_name: GFA
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04828
counters:
  proteins: 38163
  matches: 39383
  proteomes: 8672
  taxa: 15338
  structures: 4
  alphafold_models: 26902
  domain_architectures: 268
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR006913
description: The GFA enzyme catalyzes the first step in the detoxification of formaldehyde. This domain
  has a beta-tent fold [[cite:PUB00078711]].