id: Pfam:PF04950
pfam_id: PF04950
name: 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
short_name: RIBIOP_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF04950
counters:
  proteins: 8669
  matches: 8930
  proteomes: 3455
  taxa: 9157
  structures: 84
  alphafold_models: 6899
  domain_architectures: 164
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007034
description: RIBIOP_C is a family of eukaryotic proteins from the C-terminus of pre-rRNA-processing protein
  or ribosome biogenesis proteins BMS1 and TSR1. These proteins act, in the nucleolus, as a molecular
  switch during maturation of the 40S ribosomal subunit [[cite:PUB00072548],[cite:PUB00072547]]. This
  domain, domain IV of translation elongation factor selb, adopts the same fold as translation proteins
  such as domain II of GTP-elongation factor Tu proteins [[cite:PUB00038060]].