id: Pfam:PF05054
pfam_id: PF05054
name: Autographa californica nuclear polyhedrosis virus (AcMNPV) protein
short_name: AcMNPV_Ac109
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05054
counters:
  proteins: 100
  matches: 157
  proteomes: 100
  taxa: 203
  structures: 6
  alphafold_models: 92
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007748
description: This domain family is found in viral proteins such as Ac109 from Autographa californica nuclear
  polyhedrosis virus (AcMNPV). The gene (Orf1090) is essential and transcribed late in virus assembly,
  and protein AC109 has been shown to be important for the transport of the budded virion to the host
  nucleus. In mutants lacking the AC109 gene, virions are unable to enter the nucleus and remain in the
  cytoplasm. Although addition of AC109 allowed virions to enter the nucleus, the occlusion bodies were
  empty, indicating that AC109 is also important for the production of infectious budded virus [[cite:PUB00082303]]
  [[cite:PUB00082304]]. The exact function of this domain family remains unknown.