id: Pfam:PF05078
pfam_id: PF05078
name: Protein of unknown function (DUF679)
short_name: DUF679
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05078
counters:
  proteins: 4584
  matches: 4715
  proteomes: 395
  taxa: 1097
  structures: 0
  alphafold_models: 3757
  domain_architectures: 52
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007770
description: This family includes members such as plant proteins AtDMPs 1-10 (Arabidopsis thaliana DUF679
  domain membrane proteins 1 -10) [[cite:PUB00136742]]. The AtDMP proteins are predicted to have four
  transmembrane spans, with cytosolic amino- and carboxy-termini. DMP1 is a membrane protein that may
  be involved in membrane fission during breakdown of the ER and the tonoplast during leaf senescence
  and in membrane fusion during vacuole biogenesis in roots [[cite:PUB00086645]]. Several DMP proteins
  are expressed in senescing organs (DMP1, -3, -4) or tissues that will stall later in development (DMP1,
  -2, -4, -7). These expression patterns strongly suggest involvement of several DMPs in various programmed
  cell death processes, e.g. senescence, dehiscence and abscission [[cite:PUB00136742]]. AtDMP8 and AtDMP9
  however, have been shown to facilitate gamete fusion during double fertilisation in flowering plants
  [[cite:PUB00093467]].