id: Pfam:PF05092
pfam_id: PF05092
name: Per os infectivity
short_name: PIF
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05092
counters:
  proteins: 174
  matches: 174
  proteomes: 133
  taxa: 352
  structures: 0
  alphafold_models: 163
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR007784
description: This is a family of dsDNA Baculovirus proteins. It is required for the infectivity of the
  OBs or occlusion bodies. It is a structural protein of the ODV envelope required only in the first steps
  of per os larva infection, as viruses being produced in cells expressing the gene for this protein but
  not containing it in their genomes are able to produce successful infections. Baculoviruses are large
  DNA viruses that infect arthropods, mainly members of the order Lepidoptera. In their life cycle, they
  produce two kinds of particles, a budded, non-occluded virus (BV), which buds out of the infected cell
  and is responsible for the cell-to-cell transmission of the virus, and an occluded form, the occlusion
  body (OB), which is responsible for protecting the virus between encounters with larvae. A variable
  number of virions are included in the para-crystalline structure of the OB, mainly constituted by the
  virus-encoded polyhedrin protein; these virions are called occlusion body-derived virions or ODVs.
