id: Pfam:PF05430
pfam_id: PF05430
name: S-adenosyl-L-methionine-dependent methyltransferase
short_name: Methyltransf_30
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05430
counters:
  proteins: 7062
  matches: 7062
  proteomes: 6946
  taxa: 9918
  structures: 6
  alphafold_models: 4469
  domain_architectures: 11
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008471
description: This family is a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. It is often found
  in association with [pfam:PF01266], where it is responsible for catalysing the transfer of a methyl
  group from S-adenosyl-L-methionine to 5-aminomethyl-2-thiouridine to form 5-methylaminomethyl-2-thiouridine
  [[cite:PUB00043072],[cite:PUB00057501]].