id: Pfam:PF05527
pfam_id: PF05527
name: Tumor necrosis factor alpha-induced protein 8-like
short_name: TNFAIP8
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05527
counters:
  proteins: 3812
  matches: 3831
  proteomes: 1267
  taxa: 4156
  structures: 6
  alphafold_models: 3414
  domain_architectures: 24
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008477
description: This family includes human tumor necrosis factor alpha-induced protein 8-like (TNFAIP8) and
  similar proteins mainly found in animals. TNFAIP8 functions as a negative mediator of apoptosis and
  may play a role in tumour progression. Proteins in this family adopt an all-alpha configuration.