id: Pfam:PF05571
pfam_id: PF05571
name: JNK1/MAPK8-associated membrane protein
short_name: JAMP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05571
counters:
  proteins: 1738
  matches: 1806
  proteomes: 1217
  taxa: 3997
  structures: 0
  alphafold_models: 1550
  domain_architectures: 29
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008485
description: This family consists of several eukaryotic proteins including JAMP, a Jun N-terminal kinase
  1 (JNK1)-associated membrane protein. It associates with JNK1 through its C-terminal domain and regulates
  the duration of JNK1 activity in response to diverse stress stimuli [[cite:PUB00086473]]. It is an important
  component for coordinated clearance of misfolded proteins from the ER [[cite:PUB00086474],[cite:PUB00086475]].