id: Pfam:PF05742
pfam_id: PF05742
name: Transport and Golgi organisation 2
short_name: TANGO2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05742
counters:
  proteins: 10332
  matches: 10698
  proteomes: 8215
  taxa: 15243
  structures: 3
  alphafold_models: 7660
  domain_architectures: 86
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008551
description: In eukaryotes this family is predicted to play a role in protein secretion and Golgi organisation
  [[cite:PUB00075420]]. In plants this family includes [swissprot:A9X6Y0], which is involved in water
  permeability in the cuticles of fruit [[cite:PUB00075421]]. [swissprot:P54797] has been found to be
  expressed during early embryogenesis in mice [[cite:PUB00011316]]. This protein contains a conserved
  NRDE motif. This gene has been characterised in Drosophila melanogaster and named as transport and Golgi
  organisation 2, hence the name Tango2.