id: Pfam:PF05943
pfam_id: PF05943
name: EvpB/VC_A0108, tail sheath N-terminal domain
short_name: VipB
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05943
counters:
  proteins: 5453
  matches: 5471
  proteomes: 3174
  taxa: 4597
  structures: 9
  alphafold_models: 3370
  domain_architectures: 16
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR044031
description: EvpB is a family of Gram-negative probable type VI secretion system components of the tail
  sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies
  in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial
  cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches
  the target bacterial cell [[cite:PUB00075434]].