id: Pfam:PF05951
pfam_id: PF05951
name: Peptidoglycan L,D-endopeptidase MepK
short_name: Peptidase_M15_2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05951
counters:
  proteins: 3871
  matches: 3871
  proteomes: 3319
  taxa: 4791
  structures: 0
  alphafold_models: 2536
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010275
description: This family represents Peptidoglycan L,D-endopeptidase MepK from Escherichia coli and similar
  bacterial proteins. MepK cleaves meso-diaminopimelic acid cross-links in peptidoglycan. It acts in conjunction
  with other elongation-specific D, D-endopeptidases to create space for the efficient incorporation of
  nascent peptidoglycan strands into the sacculus, thereby enabling cell wall expansion [[cite:PUB00160786]].