id: Pfam:PF05970
pfam_id: PF05970
name: PIF1-like helicase
short_name: PIF1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF05970
counters:
  proteins: 26740
  matches: 27374
  proteomes: 5288
  taxa: 11185
  structures: 37
  alphafold_models: 18182
  domain_architectures: 1063
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010285
description: This family includes homologues of the PIF1 helicase, which inhibits telomerase activity
  and is cell cycle regulated [[cite:PUB00053693],[cite:PUB00053694],[cite:PUB00151827],[cite:PUB00151828]].
  This family includes a large number of largely uncharacterised plant proteins. This entry includes a
  P-loop motif that is involved in nucleotide binding.