id: Pfam:PF06075
pfam_id: PF06075
name: CORD, N-terminal domain
short_name: CORD_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06075
counters:
  proteins: 3099
  matches: 3104
  proteomes: 377
  taxa: 1031
  structures: 0
  alphafold_models: 2516
  domain_architectures: 74
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR048297
description: This domain is found at the N-terminal in Protein CORTICAL MICROTUBULE DISORDERING (CORD)
  proteins found in plants. This domain is predicted to adopt a globular structure that folds into a barrel
  similar to OB-fold barrels.CORD proteins are microtubule-associated proteins that are required, redundantly
  with CORD2, for the formation of the pitted secondary cell wall of metaxylem vessels [[cite:PUB00163241]].
  CORD1 from Arabidopsis thaliana controls the disorganisation of the parallel cortical microtubule network
  by modulating microtubule attachment to the plasma membrane in metaxylem vessel cells; this mechanism
  probably relies on disruption of interactions between ARAC10/ROP11 and cortical microtubules [[cite:PUB00163241]5].