id: Pfam:PF06090
pfam_id: PF06090
name: Inositol-pentakisphosphate 2-kinase
short_name: Ins_P5_2-kin
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06090
counters:
  proteins: 4299
  matches: 4885
  proteomes: 3187
  taxa: 8450
  structures: 23
  alphafold_models: 3623
  domain_architectures: 88
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR009286
description: This is a family of inositol-pentakisphosphate 2-kinases (EC 2.7.1.158) (also known as inositol
  1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase) and InsP5 2-kinase). This enzyme phosphorylates
  Ins(1,3,4,5,6)P5 to form Ins(1,2,3,4,5,6)P6 (also known as InsP6 or phytate). InsP6 is involved in many
  processes such as mRNA export, nonhomologous end-joining, endocytosis and ion channel regulation.