id: Pfam:PF06162
pfam_id: PF06162
name: Putative pyroglutamyl peptidase PgaPase_1
short_name: PgaPase_1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06162
counters:
  proteins: 166
  matches: 174
  proteomes: 112
  taxa: 491
  structures: 0
  alphafold_models: 157
  domain_architectures: 8
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010381
description: PgaPase_1 is a family of functionally diverse Caenorhabditis proteins. The family is homologous
  to the cysteine-peptidases, but lack of a strictly conserved Glu-Cys-His catalytic triad or pGlu binding
  site implies that it has other functions that could have resulted in a change in reaction-specificity
  or even of catalytic activity [[cite:PUB00075353]].