id: Pfam:PF06255
pfam_id: PF06255
name: Neisseria toxin MafB
short_name: MafB
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06255
counters:
  proteins: 42
  matches: 42
  proteomes: 12
  taxa: 30
  structures: 0
  alphafold_models: 36
  domain_architectures: 8
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR064118
description: MafB constitutes a family of secreted toxins in pathogenic Neisseria species, probably involved
  in interbacterial competition [[cite:PUB00073618]]. Genes immediately downstream of mafB encode a specific
  immunity protein (MafI). MafB proteins exhibit a signal peptide sequence, a N-terminal conserved domain
  and a C-terminal variable region. Toxic domains identified at the C terminus include [pfam:PF15542],
  [pfam:PF14437], [pfam:PF15524], and [pfam:PF14436].