id: Pfam:PF06283
pfam_id: PF06283
name: Trehalose utilisation
short_name: ThuA
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06283
counters:
  proteins: 17609
  matches: 17981
  proteomes: 6386
  taxa: 9304
  structures: 4
  alphafold_models: 10006
  domain_architectures: 446
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR029010
description: This family consists of several bacterial ThuA-like proteins. ThuA appears to be involved
  in utilisation of trehalose [[cite:PUB00013786]]. The thuA and thuB genes form part of the trehalose/sucrose
  transport operon thuEFGKAB, which is located on the pSymB megaplasmid. The thuA and thuB genes are induced
  in vitro by trehalose but not by sucrose and the extent of its induction depends on the concentration
  of trehalose available in the medium [[cite:PUB00109706]]. ThuA is involved in the conversion of of
  disaccharides to their respective 3-keto derivatives [[cite:PUB00076441]].