id: Pfam:PF06381
pfam_id: PF06381
name: Phage portal protein
short_name: Phage_portal_3
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06381
counters:
  proteins: 1449
  matches: 1451
  proteomes: 1186
  taxa: 2536
  structures: 13
  alphafold_models: 637
  domain_architectures: 16
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024459
description: This family represents phage and prophage portal proteins that form the portal of the phage
  particle [[cite:PUB00155786],[cite:PUB00153918],[cite:PUB00154413]]. These proteins form a dodecamer
  assembly that defines a channel for DNA entry and exit. The dodecamer structure resembles a flying saucer
  with a central channel, which is filled with a rope-like DNA chain [[cite:PUB00154413]]. Each subunit
  of the dodecamer is involved in interaction with capsomers. The dodecameric portal is connected with
  the neck, which comprises a dodecameric adaptor, a hexameric connector, and a hexameric terminator gp12,
  forming a continuous DNA injection channel at the center [[cite:PUB00154413]].