id: Pfam:PF06382
pfam_id: PF06382
name: Protamine and protamine like
short_name: Protamine_like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06382
counters:
  proteins: 239
  matches: 275
  proteomes: 83
  taxa: 372
  structures: 0
  alphafold_models: 214
  domain_architectures: 8
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024460
description: This family consists of several insect proteins including protamine A (ProtA), protamine
  B (ProtB) and protamine-like protein 99C (Prtl99C) from Drosophila melanogaster. They contain a HMG-box
  and are involved in chromatin compaction during spermiogenesis [[cite:PUB00083892],[cite:PUB00083890]].
  Prtl99C is a sperm chromatin-associated protein that is essential for male fertility [[cite:PUB00083890]].