id: Pfam:PF06439
pfam_id: PF06439
name: 3-keto-alpha-glucoside-1,2-lyase-like domain
short_name: 3keto-disac_hyd
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06439
counters:
  proteins: 19525
  matches: 21475
  proteomes: 4164
  taxa: 6169
  structures: 18
  alphafold_models: 12269
  domain_architectures: 757
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR010496
description: This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside
  hydrolase family 16. A member containing this domain, BT2157 from B. thetaiotaomicron [[cite:PUB00097337]],
  was initially described as a 3-keto trehalose hydrolase involved in trehalose degradation [[cite:PUB00097337]].
  However, members of this group of proteins, previously known as DUF1080, have been reported to be 3-keto-alpha-glucoside-1,2-lyases
  and 3-keto-2-hydroxy-glucal hydratases and named AL/BT2 enzymes [[cite:PUB00160473]].