id: Pfam:PF06577
pfam_id: PF06577
name: Envelope integrity protein A
short_name: EipA
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06577
counters:
  proteins: 1554
  matches: 1554
  proteomes: 1534
  taxa: 2053
  structures: 1
  alphafold_models: 1006
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008325
description: This family includes envelope integrity protein A (EipA), a protein required for B. abortus
  envelope stress resistance and infection. It's gene expression is directly activated by CtrA which binds
  to the promoter region. eipA encodes a soluble periplasmic protein that adopts an unusual eight-stranded
  beta-barrel fold [[cite:PUB00091721]].