id: Pfam:PF06740
pfam_id: PF06740
name: Microtubule associated protein Futsch
short_name: MAP_Futsch
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF06740
counters:
  proteins: 44
  matches: 1209
  proteomes: 33
  taxa: 156
  structures: 0
  alphafold_models: 3
  domain_architectures: 32
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR009603
description: The Drosophila protein Futsch has homology to MAP1B and controls synaptic growth at the Drosophila
  neuromuscular junction through the regulation of the synaptic microtubule cytoskeleton. Ftusch protein
  colocalises with microtubules and identifies cytoskeletal loops that traverse the lateral margin of
  select synaptic boutons. Futsch mutations disrupt synaptic microtubule organisation. The N- and C-terminal
  domains of Futsch are homologous to the vertebrate MAP1B microtubule-associated protein. The central
  domain of Futsch is highly repetitive and it is represented in this entry [[cite:PUB00059957]].